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Long term Denosumab Use Shows Favorable Outcomes: Results from the FREEDOM Extension Trial

Osteoporosis is a disease characterized by increased bone loss that outpaces the grown of new bone. As a result bones become less dense and more fragile and brittle; porous bones are more prone to fracture.

DSB: Drug Shortages July 2015

Several drugs continue to be in short supply, posing significant problems for patients. Foremost on this list is leflunomide (Arava) which is backordered for both 10 mg and 20 mg tablets.  

Leflunomide Shortage

Allopurinol Risky in Asian Population

The go-to drug to treat hyperuricemia and gout, allopurinol, put patients at risk for developing hypersensitivity when American College of Rheumatology guidelines weren't followed, a large database study found.

Rituximab Induced Serum Sickness

Karmacharya and colleages have reviewed 33 cases of rituximab-induced serum sickness. Half of these patients had the classic triad of SS fever, rash, and arthralgia and a self-limiting course. The time to onset after infusion was greater with the first dose of rituximab c

Residents Satisfied and Optimistic

Recently released 2015 Medscape resident salary & debt report shows that most medical residents are satisfied with their compensation, professional relationships, and career choices.

Increasing Age May Increase Miscarriage Risk in RA

At EULAR 2015, Brouwer and colleagues reported on their cohort of 162 evaluable pregnancies in 239 Dutch women enrolled during 2002-2010 in the nationwide Pregnancy-Induced Amelioration of Rheumatoid Arthritis (PARA) study – a large prospective cohort of pregnant RA patients.

Women Paid Less as Consultants to Pharma... Again?

Historically, women’s salaries have lagged behind their male colleagues. Women are less likely to achieve leadership roles or be full professors at academic institutions.

Does Antibiotic Exposure Increase the Risk of JIA?

According to the CDC, between 4300 and 9700 children under the age of 16 are diagnosed with juvenile idiopathic arthritis each year - the cause of which is unknown.

IL-1 Inhibition May Be an Alternative Treatment for Behcet's

Behcet's disease is difficult to manage, especially if the goal is to avoid corticosteroids.

Alpha-1-Anti-Trypsin-Fc Fusion Protein Ameliorates Gouty Arthritis

Gout is the most common inflammatory arthritis affecting adults and, probably, one of the most underestimated.

Lithium May Have Chondroprotective Effects in OA

Several studies have suggested that lithium chloride exhibits significant chondroprotective effects on cartilage degradation (in animal models) in response to inflammatory cytokines.

The Spread of Lyme Disease in the US

It is estimated that Lyme disease affects nearly 30,000 per year in the USA. While it is is still a disorder of the Northeast and upper Midwest, there are more areas also considered to be high risk.

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