The British Medical Journal reports that the combined use of NSAIDs and anti-depressants were associate with higher rates of intracranial bleeding within 30 days of initiation (Citation source http://buff.ly/1gF3uEJ).
FDA Scours the Internet for Safety Signals. A Bloomberg News report shows how the FDA is using Google or Yahoo keyword searches to identify new safety signals or drug interactions, often more than a year before they were brought to light by the FDA based on prior methodologies de
The Journal of Clinical Investigation has written a tribute noting the sad passing of Dr. Norman Talal on April 24, 2015.
Dr. Talal was an eminent researcher and clinician known for his research and education on Sjogren’s syndrome.
A systematic review of treatments used in autoimmune chronic uveitis after failure of DMARDs and at least one TNF inhibitor identified few patients (12 children and 34 adults), and few trials examining rituximab (3), abatacept (3), tocilizumab (3), and 1 each with alemtuzumab and anakin
The MedWatch June 2015 safety labeling changes were published yesterday, and updated the warnings for Xeljanz (tofacitinib). "The risk of herpes zoster is increased in patients treated with Xeljanz and appears to be higher in patients treated with Xeljanz in Japan."
Committees at academic institutions that make decisions on research and clinical trials may be conflicted, as nearly one-third of IRB members have some ties to the pharmaceutical industry.
On Friday, July 10th, the U.S. House voted overwhelmingly to streamline the approval process of prescription drugs and medical devices by the FDA.
Defects in protein citrullination and its consequences in patients with RA have been studied widely in the recent decade. It appears that autoantibodies, including those against citrullinated proteins, are of diagnostic and prognostic relevance.
One million people are hospitalized each year with sepsis. This is more than the number of hospitalizations for heart attack and stroke combined. Sepsis can be a particular risk for older people.
Researchers have determined that adults aged 50 and above were more likely to acquire pain relievers through more than one doctor, whereas younger individuals were more likely to acquire them from friends, relatives or drug dealers.
FDA announced yesterday they would strengthen warnings stating that non-aspirin nonsteroidal anti-inflammatory drugs increase the chance of a heart attack or stroke. This applies to both prescription and OTC NSAIDs.
A slim, yoga bending, middle aged school teacher seeks a rheumatology consultation to determine the cause and cure for her left lateral heel pain for the past 6 months. No trauma, no crazy footwear and no systemic symptoms, uveitis, or peripheral/axial arthritis.
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