Bullous Systemic Lupus Erythematosus (BSLE) BSLE is a rare blistering cutaneous manifestation of systemic lupus erythematosus (SLE). As goes SLE, bullous disease typically affects women, especially those of African descent. https://t.co/TBr7pGXjZ5 https://t.co/aq5dX3wQPX