Difficult to treat RA? #EULAR2022 1) Active/progressive disease, unable to taper steroids, radiographic progressive, decreased QoL 2) Failure of medications (2+ b/tsDMARD after csDMARD) 3) Physician/patient perception - Fatigue: not part of definition ~5-20% pts @Rheumnow https://t.co/i5sfwoF2Gs