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No Correlation Between Urate Crystal Identification and Cardiovascular Risk

A Danish cohort study examined patients with hyperuricemia  and compared outcomes in those proven to have urate crystal deposition (317 patients) and matched 1:1 to patients without urate crystals.

Study Backs CellCept for ILD in Scleroderma

MONTREAL -- An immunosuppressive drug was as effective as a standard agent for interstitial lung disease (ILD) associated with scleroderma, a researcher said.

ANCA Levels Predict Relapse in ANCA-Associated Vasculitis

A team of Japanese investigators examine 126 patients with ANCA-associated renal vasculitis to see if ANCA levels would predict disease relapse.

Downward Trends in US Mortality Statistics

Using death certificate data from US National Vital Statistics System of the National Center for Health Statistics (NCHS) and the Centers for Disease Control and Prevention, JAMA reports a downward trend in death rates in the USA from 1969 - 2013).

Obamacare Deficient in Rheumatologists, Other Specialists

The October 27 issue of JAMA reports a study of federal marketplace insurance plans shows roughly 15 percent completely lacked in-network physicians for at least one specialty, a practice found among multiple states and issuers.

High Level Skin Responses Seen with Inhibitor of IL-23p19 in Psoriasis

Rheumatology News reports the results of a novel trial presented at the European Academy of Dermatology and Venereology meeting in Copenhagen.

FDA Panel Votes 10-4 to Approve Lesinurad for the Treatment of Hyperuricemia/Gout

Despite concerns over safety, the FDA Arthritis Advisory Committee voted favorably to approve lesinurad (LES) at a meeting held Friday, October 23, 2015. Overall, panel members felt the potential benefits of LES outweighed the safety concerns reviewed by the FDA presenters.

Vertebral Fractures in 10% of Spondyloarthritis Patients

Vertebral fractures are not uncommon in patients with ankylosing spondylitis and spondyloarthritis.

IV Cyclophosphamide Equal to Mycophenolate in Lupus Nephritis

A comparison of mycophenolate mofetil (MMF) and low-dose cyclophosphamide IV (CYC) in the treatment of lupus nephritis (LN) was examined in 173 patients with class III, IV, or V LN.

Increasing Placebo Responses in the USA

A recent analysis of randomized clincal trials (RCT) for the treatment of neuropathic pain has shown in increase in placebo responses. (Citation source http://buff.ly/1LL8yAi)

MMP-3 Levels Predict Radiographic Progression in RA

Continuously elevated serum matrix metalloproteinase-3 (MMP-3) for 3-6 months predicted 1-year radiographic progression in rheumatoid arthritis (RA), according to a small prospective cohort study in Arthritis Researc

U.S. Pays 10 Times More for Prescription Drugs than Other Countries

Prescription drugs may cost up to 10 times more in the United States than they do in other countries, according to a 2013 Comparative Price Report was released last month by the International Federation of Health Plans (IFHP).

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