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Young Lupus Patients Have Higher Mortality Risk

A retrospective study examined mortality rates by comparing 2740 UK lupus patients  who were matched 1:4 with controls from the UK Clinical Practice Research Datalink between 1999 and 2012. (Citation source http://buff.ly/1nJWKIT)

Should You Avoid Pneumococcal Vaccine in CAPS and Behcet's Patients

Althought EULAR currently recommends the pneumococcal vaccine be given to patients with inflammatory rheumatic diseases and the Centers for Disease Control and Prevention (CDC) recommends the vaccine in patients treated with immunosuppressive drugs, a recent brief report suggests it be

Increased Congenital Anomalies in Children from Women with a Juvenile Arthritis History

A Quebec administrative claims analysis examined the birth outcomes of women with a history of juvenile idiopathic arthritis (JIA) who subsequently had a first-time birth (between 1983-2010).

Cochrane Review:NSAIDs Equally Effective for Axial Spondyloarthritis

Until the advent of TNF inhibitor therapy, nonsteroidal antiinflammatory drugs (NSAIDs) were the only effective treatment for ankylosing spondylitis or spondyloarthritis (SpA).  More recently, several reports have suggested clinical and radiographic benefits to sustained NSAID use.

Rheumatoid Arthritis, TNF inhibitors and the Risk of Skin Cancer

Rheumatoid arthritis (RA) patients are said to have a neutral risk for neoplasia, but this is because they have a lower risk of colon cancer and breast cancer but a higher risk of lung cancer, lymphoma and skin cancers.

High 14-3-3η Levels Have Predictive Value in Early Inflammatory Arthritis

14-3-3η is a new serum assay that has utility in diagnosing and treating patients with rheumatoid arthritis (RA) and early inflammatory arthritis (EIA).

Comorbidities Start Early in Rheumatoid Arthritis

A Northern Sweden early rheumatoid arthritis (RA) cohort of 950 patients was enrolled starting in 1995. A validated questionnaire at RA onset (T0) and after 5 years (T5) after enrollment. Currently, 726 of these have had RA for ≥5 years.

No Significant Increased Risk with TNF Inhibitors During Pregnancy

A population-based study of 1,272,424 live-born infants from Denmark and Sweden examined the prevalence of birth defects among infants born to 683 women with chronic inflammatory disease (inflammatory bowel disease, rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, or psoriasis)

Biosimilar of Remicade Works in Ankylosing Spondylitis

CT-P13, a biosimilar of infliximab (Remicade), demonstrated comparable and durable efficacy in the treatment of ankylosing spondylitis (AS), a multinational study found.

ANA Negative Lupus Nephritis - Does it Exist?

A recent report from the Mayo Clinic describes a 49 year-old patient with lupus nephritis who presented with new-onset hypertension, edema, arthritis, serositis and leukocytoclastic vasculitis, and who later developed glomerulonephritis and nephrotic syndrome.

Ultrasound Predicts Inflammatory Arthritis in CCP+ Persons Without Synovitis

A prospective study of 136 people who were CCP+, but who had no clinical evidence of synovitis, examined what factors may predict future development of inflammatory arthritis.

NIH-Funded Trials Down, While Industry Trials Increase

(Reuters Health) – Every year since 2006 in the U.S., the amount of new medical research in humans funded by the National Institutes of Health (NIH) has gone down, while the number of industry-funded trials has gone up, a new study shows. 

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