Hemochromatosis Reviewed
Powell et al have published in Lancet a review of hemochromatosis; its genetics, pathogenesis, clinical manifestations and management.
News
MMWR Update on Zika Virus: 116 US Cases Related to Travel
The Centers for Disease Control and Prevention (CDC) reported that in the last year (January 2015 to February 2016), they have identified and confirmed 116 cases of the Zika virus among US residents, with nearly all having traveled to endemic regions.
Differences in Diuretic-Induced Gout
Diuretics are frequently implicated causes of hyperuricemia and gout. And there are gout variants wherein age, renal dysfunction and diuretic use may give rise to gouty attack in the hands of women with nodal osteoarthritis.
The Week in Review 18 March 2016
See the highlights from the past week that appeared on RheumNow.com, and watch Dr. Jack Cush as he reviews each of them.
Does Your Hospital Staff Include a Donald Trump?
When Donald Trump announced that he was running for president last summer, most people didn't know quite what to think. Was this serious or some sort of publicity stunt? Would he be in the race for more than just a few weeks of intense media spotlight?
Bisphosphonate Use Falls Following FDA Warnings
In the current issue of JBMR, Kim and colleagues from Brigham and Women's Hospital in Boston assessed US claims data and studied the impact of three FDA drug safety warnings regarding the use of bisphosphonates.
Acetaminophen: No Effect in Osteoarthritis Pain or Function
A network analysis of multiple therapies used in osteoarthritis found that acetaminophen (paracetamol) does not meet the minimum standard of clinical effectiveness in reducing pain or improving physical function in patients with knee and hip osteoarthritis.
January/February 2016 Top Social Media News
In February 2016, RheumNow published 82 tweets about impactful news, research and teaching points that impact the rheumatology community. These feeds had a reach (impressions) of 80,800 with, 76 mentions, and over 2700 visits to learn on RheumNow.com.
Sclerostin Inhibition May Worsen Rheumatoid Arthritis
Sclerostin, an inhibitor of the Wnt/β-catenin pathway, negatively regulates osteoblast differentiation and has anti-anabolic effects on bone formation. Thus, inhibition of sclerostin is currently being studied as therapy for postmenopausal osteoporosis.
TNF Inhibitors Increase Perioperative Infection Risk
The use of tumour necrosis factor α inhibitors (TNFis) at the time of major surgery has been a challenge for surgeons, rheumatologists and those wishing to develop evidence-based guidelines for this clinical scenario.
IL-6 Inhibition Makes News
Several new interleukin-6 inhibitors made headlines this week. While none of the new IL-6 inhibitors are soon to be approved and available, these studies may redefine the role of other non-TNF biologics in the future.
News Bytes
Most medical school faculty don't have time to observe third- and fourth-year medical students doing a complete medical exam? In When Medical Students Push Back, Westby Fisher, MD, FACC, offers his take on unnecessary testing and this particular issue.
