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FDA Biosimilar Approval of Inflectra Viewed as a Milestone Advance

On February 9th, the Food and Drug Administration (FDA) Arthritis Advisory Committee voted 21-3 in favor of approving the infliximab biosimilar, CT-P13/Inflectra, for use in all of infliximab's indications.

Cardiology Anti-inflammatory Trial Fails to Improve CV Outcomes

Researchers at Brigham and Women's Hospital, Boston evaluated the efficacy and safety of the anti-inflammatory drug losmapimod on cardiovascular outcomes given to patients with a history of myocardial infarction and CV risk factors.

EUSTAR Analysis Yields Predictors of Skin Improvement in Diffuse Systemic Sclerosis

Systemic sclerosis is one of the most challenging of rheumatic diseases, often complicated by significant morbidity and leads to irreversible disability in many cases.

ACC Publishes Guidelines for Non-Statin Therapies

The American College of Cardiology has released its expert consensus guidance regarding the use of non-statin therapies to lower cholesterol in high-risk patients.

Severe Psoriasis Associated with a Renal Disease Risk

There have been several reports of psoriasis being linked to chronic renal disease in the literature. Another population-based study has also found a link between severe psoriasis and kidney disease. 

Treating OA Knee Effusions with Low-Dose Spironolactone

Knee effusions in osteoarthritis are estimated to occur in 44% of patients, and more than half of these are painful.  Management of knee OA with effusions can be problematic given the treatment options and the high recurrence rate.

The Week in Review - 1 April 2016


Highlights from this week on RheumNow.com

Opioid Use in Rheumatoid Arthritis

Opioid use and abuse is at an all time high. Epidemiologic and public health analyses have led to greater stringency and attempts to limit use have adversely effected those with arthritis.

Baricitinib Benefits Refractory RA

The small molecule oral JAK inhibitor baricitinib was effective for patients with highly refractory rheumatoid arthritis, a phase III study found.

Incidence of Psoriatic Arthritis Among Psoriasis Patients

Researchers at the University of Toronto have prospectively studied a cohort of 464 psoriasis patients without a diagnosis of arthritis and followed them over 8 years to estimate the incidence and frequency of psoriatic arthritis (PsA). 

Antibiotics Fail to Treat Chronic Symptoms of Lyme Disease

(Reuters Health) - Twelve weeks of antibiotic therapy proved ineffective at combating the long-term symptoms seen in some people who have had Lyme disease, a new test of 280 sufferers found. (Citation source http://buff.ly/1Rs21R5)

Drug Safety Bulletin - March 2016

RheumNow is committed to reporting safety issues in our monthly Drug Safety Bulletins, wherein we will update you with reports of new, ongoing and resolved Drug Shortages that will affect rheumatology.   If you have suggestions or information about specific drug sho

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