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Tocilizumab Effective in PMR

Polymyalgia rheumatica (PMR) should be easy and responsive, but it can be a challenge and requires long-term steroid therapy. Problems often begin when steroid–induced side effects take their toll on a patient, especially in elderly adults.

Opioid Prescriptions in Decline

In an era of increasing fears over narcotic abuse and narcotic-related deaths, the number of opioid prescriptions in the United States is finally falling, the according to the NY Times. 

TB Management Questions

The following is a compilation of several frequently asked questions regarding tuberculosis (TB) testing or treatment in patients on a TNF inhibitor (TNFi) or other biologic agents.

ORBIT Study Shows Rituximab and TNF inhibitor Equivalence

The initial choice of biologic is crucial to long-term success. Yet there are few studies evaluating head-to-head differences in some of our most popular therapies.

RheumNow Week in Review - 19 May 2016

Dr. Jack Cush reviews this week's news and research highlights from RheumNow.com.

FDA Delays Ruling on Generic Labeling

The New York Times reports that the FDA has delayed its much anticipated ruling on generics until sometime in 2017. 

Musculoskeletal Complications of Hematologic Disorders Reviewed

Morais and colleagues have published an informative review of rheumatologic and musculoskeletal (MSK) disorders that may potentially befall those with benign or malignant blood disorders. It is important to be aware of these associations.

GWAS Reveals Shared Susceptibility Locus Between RA and SLE

While the phenotypes of RA and SLE are quite different, genome-wide association studies (GWAS) performed in the past have shown a genetic overlap between both.

Risk Factors for Bisphosphonate Bone Complications

Rare reports of bisphosphonate associated atypical femoral fractures (AFF) and osteonecrosis of the jaw (ONJ) have raised concerns about the chronic use of bisphosphonates. The risk of AFF and ONJ was assessed in an analysis of the Swedish national database.  

Reports Call for More Gout Education

Two recent surveys show that gout patients are often uninformed, undertreated, improperly monitored and frequently stigmatized by their gout.

Cochrane Reports Moderate Evidence Favoring Biologic Add-on Therapy

Singh and coworkers have assessed the value of adding a biologic to rheumatoid arthritis (RA) patients not responding to either methotrexate (MTX) or DMARDs. The results of their netowork metanalsysis is published as a Cochrane review wherein they examined a total of 90 RCTs (73 new) with 32

Netrin-1 May Promote Lung Fibrosis in Scleroderma

Mechanisms underlying the pulmonary fibrosis of systemic sclerosis are poorly understood, yet are the focus of both research and new drug development. 

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