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No Arthroscopy Needed for Degenerative Knees and Meniscal Tears

The British Medical Journal has published a clinical practice guideline for the use of arthroscopic surgery for degenerative knee arthritis and meniscal tears, suggesting that many patients will not benefit from such surgery.

Rituximab May Benefit Rheumatoid Lung

A retrospective study shows that rituximab treatment of RA-related interstitial lung disease may improve or forestall ILD progression.

The RheumNow Week in Review – 12 May 2017

Dr. Jack Cush highlights the big stories, news and articles from this week at RheumNow.com.

Adalimumab Effective in Pediatric Plaque Psoriasis

Adalimumab is currently FDA approved for use in adult psoriasis, pediatric Crohn's disease and polyarticular juvenile idiopathic arthritis.  The current Lancet trial assesses the efficacy and safety of adalimumab in children and adolescents with severe plaque psoriasis.

NSAIDs Increase Risk of Acute Myocardial Infarction

Using data from Canadian and European healthcare databases, the BMJ has reported that all NSAIDs, including celecoxib and naproxen, increase the risk of acute myocardial infarction.

One-Third of FDA Approvals Need Post-Marketing Safety Changes

One-third of newly approved drugs in the next decade will require new safety warnings based on pharmacovigilance, according to a new study in JAMA. (Citation Source: http://buff.ly/2r3dYUs)

High Mortality with ANCA Associated Vasculitis

Mortality remains high in patients with the types of vasculitis that are associated with the presence of antineutrophil cytoplasmic antibodies (ANCA), a meta-analysis in Annals of the Rheumatic Diseases determined.

Above-Label Dosing and Noncompliance with Biologics in Psoriatic Arthritis

Claims data analysis of 4245 psoriatic arthritis patients on TNF inhibitors showed both higher than expected durations of noncompliance and higher than label dosing - all at an increased cost.

ACP Guideline Recommends Generic Bisphosphonates But Limits DEXA Use

The American College of Physicians (ACP) has updated its 2008 clincial practice guideline on the treatment of low bone density and osteoporosis to prevent fractures in men and women.  The new guideline is in favor of generic bisphosphonate use and recommends against using menopausal estrogen therapy and against DEXA monitoring during the first 5 years.

CDC Shows a 40% Lifetime Risk of Symptomatic Hand Osteoarthritis

Qin and colleagues have published in Arthritis & Rheumatology that 40% of people will be affected by symptomatic osteoarthritis in at least one hand.  (Citation source: http://buff.ly/2qTUscZ)  

Calcium Supplements and Cardiovascular Risk

Dr. Nancy Lane answers questions about the intake of Calcium, Vitamin D and the cardiovascular risk of supplemental calcium.

Increased Comorbidities in Rheumatoid Arthritis

A population based study from Taiwan examined the frequencies of comorbidities in a rheumatoid arthritis (RA) population.

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