Is High Dose Aspirin Needed in Kawasaki Disease?

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Does aspirin add any advantage to intravenous immunoglobulin (IVIG) alone in children with Kawasaki disease (KD)?

EMR Messaging Woes (4.11.2025)

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Dr. Jack Cush reviews the news, journal reports and regulatory approvals from this past week on RheumNow.com

Should Lupus Nephritis Receive PJP Prophylaxis?

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A current review article suggests that the need for Pneumocystis jirovecii pneumonia (PJP) prophylaxis in patients with systemic lupus erythematosus (SLE) and lupus nephritis will need to be individualized based on therapies and risk factors. 

Pregnancy-Related Deaths in the US

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A CDC cross-sectional national study showed an increase in pregnancy-related deaths in the US from 2018 to 2022, with highest rates among American Indian, Alaska Native women, and non-Hispanic Black women. 

Yoga vs Strengthening Exercise in Knee Osteoarthritis

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A randomized clinical trial in knee osteoarthritis (KOA) patients showed both yoga and strengthening improved knee pain over 12 weeks, with no difference between groups.

RA Prevention through Deep Immunophenotyping

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Researchers at the University of Colorado have identified pathogenic immune phenotypes in at-risk populations for rheumatoid arthritis (RA).

Uveitis Risk with Slow Adalimumab Weaning

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Patients with pediatric non-infectious uveitis (NIU) who achieved remission on adalimumab (Humira) had lower recurrence rates when the drug was withdrawn more gradually, a retrospective cohort analysis indicated.

ACP: Best Practice Advice on Cannabis or Cannabinoids Use for Chronic Noncancer Pain

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The American College of Physicians published a best practice advisory on cannabis or cannabinoids in the Annals of Internal Medicine.

Mindfulness and CBT improve chronic low back pain

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Behavioral interventions were associated with reduced pain and daily opioid use and improved function and quality of life for up to 12 months among adults with opioid-treated chronic low back pain, according to a new randomized clinical trial.

An Epidural Letdown (4.4.2025)

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Dr. Jack Cush reviews the news and journal reports from this past week on RheumNow.com.

Vamorolone: a New Steroid on the Horizon?

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Steroids, Prophylaxis and Pneumocystis Pneumonia

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A case-control study has shown that glucocorticoids and tapering glucocorticoids are risk factors for the development of Pneumocystis jirovecii pneumonia (PJP).