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New Side Effect From mRNA COVID Vaccines?

MedPage Today

Herpes zoster reactivation -- a.k.a. shingles -- following COVID-19 vaccination in six patients with comorbid autoimmune/inflammatory diseases may be a new adverse event associated with the Pfizer/BioNTech mRNA vaccine, suggested a new report.

Raynaud and Microvascular Complications with New Migraine Meds

A new study of calcitonin gene-related peptide (CGRP) antagonists for migraine headaches found that a small subset manifested Raynaud phenomenon and other had microvascular complications, suggesting that CGRP antagonists should be used in caution in patients with Raynauds. 

Dr. Charles Christian of HSS Honored

In the current issue of Annals of Rheumatic Disease, Dr. Peggy Crow honors the life and career of one the great, historic rheumatologists of all time: Dr. Charles Christian. For those interested in the history of rheumatology, mentoring and leadership, this is a good read. For those interested in leading a truly good life, and being a real role model, this is a must read.

Broadalumab Efficacy in Axial Spondyloarthritis

Broadalumab (Siliq), an anti-interleukin-17 receptor A monoclonal antibody, is currently FDA- approved for use in adults with plaque psoriasis; but a recent trial shows it to be effective in patients with axial spondyloarthritis (axSpA).

New, Improved Therapy for Pompe Disease

Researchers from the University of Cincinnati Gardner Neuroscience Institute will present data on a new treatment for Pompe disease at the American Academy of Neurology on April 20th; the results show that treatment with avalglucosidase alfa yielded substantial clinical improvements and a more favorable safety profile compared to the current standard of care (alglucosidase alfa).

RheumNow Podcast – Combination Biologics

Dr. Jack Cush serves up this week's news and articles from RheumNow.com.

Planes, Trains and COVID Distancing

MMWR reports the risk of acquiring an infection with SARS-CoV-2 is reduced 23% to 57% when the middle seat was vacant (compared with full aircraft occupancy).

Autoimmune Risk of Death Up during COVID

A population-based study in the UK shows that patients with rare autoimmune rheumatic diseases (RAIRD) were 44% more likely to die during the 2020 COVID-19 pandemic (March - April) compared to either the general population or their pre-COVID risk.

USPSTF - No Need to Screen for Vitamin D Deficiency

JAMA has published the new recommendation from the US Preventive Services Task Force (USPSTF) stating that screening for vitamin D deficiency is unnecessary and unwarranted in asymptomatic adults.

NICE Guidelines on Chronic Pain Management

In the United Kingdom, where it is estimated that chronic pain affects one‑third to one‑half of the population, NICE (National Institute for Health and Care Excellence) has recently released an updated guideline on the management of chronic pain for people aged 16 years and over.

Sinusitis Activity Linked to Brain Dysfunction

Have you wondered why fibromyalgia, fatigue or cognitive dysfunction often co-associate with chronic sinusitis?

IL-23 Targeting for Enthesitis in Psoriatic Arthritis

MedPage Today

Treatment with guselkumab (Tremfya) was effective in resolving enthesitis among patients with psoriatic arthritis (PsA), a post-hoc analysis of two phase III trials found.

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