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Does Methotrexate Increase Skin Cancer Risk?

There are several reports suggesting a link between methotrexate (MTX) use and certain skin cancers, yet these are confounded by a higher risk of skin cancers with inflammatory conditions like rheumatoid arthritis of which MTX is the most common treatment.

Deucravacitinib - Effective in Systemic Lupus Erythematosus

A Phase II, multicenter study has demonstrated the efficacy and safety of deucravacitinib, an oral, selective, allosteric inhibitor of TYK2, in  adults with active systemic lupus erythematosus (SLE).

Serious Infection Risk in Pediatric Psoriasis with Ustekinumab, Etanercept, or Methotrexate

Etanercept was FDA approved for use in pediatric psoriasis (PsO) in 2016 and ustekinumab was similarly approved  in 2020.  This comparative analysis looks at the risk of serious infections (SIE) requiring hospitalization in pediatric PSO patients treated with ustekinumab, etanercept, or

New 5 Peptide Autoantibody Panel Complements RA Diagnosis

MedPage Today

Antibodies to peptides not currently used for rheumatoid arthritis (RA) diagnosis helped identify patients with untreated early disease that conventional biomarkers missed, researchers said.

GRAPPA Recommendations for Treating Enthesitis in Psoriatic Arthritis

GRAPPA has provided new, evidence based updates to the management of enthesitis in patients with psoriatic arthritis (PsA), affecting at least 30% of PsA patients and is associated with more severe disease, x-ray damage, and poorer outcomes. 

ICYMI: GRAPPA Recommendations for Treating Enthesitis in Psoriatic Arthritis

GRAPPA has provided new, evidence based updates to the management of enthesitis in patients with psoriatic arthritis (PsA), affecting at least 30% of PsA patients and is associated with more severe disease, x-ray damage, and poorer outcomes. 

ChatGPT - A Boon or Threat to Scientific Publication?

ChatGPT is a new, artificial intelligence chatbot that has dramatically changed the digital worlds of education, research, graphic design, statistics and more.

High- Versus Low-Dose Exercise Therapy for Knee Osteoarthritis

Exercise is known to improve function, pain and quality of life (QOL) in patients with knee osteoarthritis (KOA), but optimal amount of exercise is unknown.

Burnout #10 (2.3.2023)

Dr. Jack Cush reviews the past week of news on RheumNow.com.

Novel Proteomic Biomarker Set in Osteoarthritis

NIH funded researchers from Duke University have developed a set of serum proteomic biomarkers that successfully predict clinically relevant knee osteoarthritis (KOA) progression (both structural change and joint pain) over a 2 year period.

Physician Burnout Remains, Less So in Rheumatology

The 2023 Medscape Survey on Physician burnout ranks rheumatology at #10; which is down from #2 when the survey was last done in 2021.

ACR Urges CMS to Reconsider Copay Assistant Programs in CMS Proposed Rule

The Health and Human Services Notice of Benefit and Payment Parameters proposed rule for 2024 does not revise policies related to copay assistance and patient deductibles.

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