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      A large prospective psoriatic arthritis (PsA) study examined the enthesitis outcomes when PsA patients received conventional (cDMARDs) or targeted disease-modifying antirheumatic drugs (tDMARDs) and showed an overall 86% response rates, regardless of the medication used.
      French study from 362 septic arthritis pts over 2 yrs., mean age was 64yrs, w/ high Charlson comorbidity index 3.5. Most

      Dr. John Cush RheumNow

      3 years 5 months ago
      French study from 362 septic arthritis pts over 2 yrs., mean age was 64yrs, w/ high Charlson comorbidity index 3.5. Most common was Knee (39%), Staphylococcus (51%), Abx used 47d, surgery in 48%; 28% serious complications & 9.2% died https://t.co/P2nxnhDnut https://t.co/KoZoe1yib4
      The concept of a “Still’s disease continuum” that encompasses both sJIA and AOSD is based on the many common clinical, genetic and laboratory features shared by both sJIA and AOSD.
      162 #AOSD or #sJIA criteria+ pts underwent genetic testing - 31% (51/162) had a genetic variant for periodic fever Dx. 4

      Dr. John Cush RheumNow

      3 years 5 months ago
      162 #AOSD or #sJIA criteria+ pts underwent genetic testing - 31% (51/162) had a genetic variant for periodic fever Dx. 4 SJIA pts were confirmed to have FMF or TRAPS. Genetic testing may be smart, esp w/ atypical presentations https://t.co/hwZFgOL4j4 https://t.co/6y8r1Dyv1A
      Abatacept Most Effective Early and in Seropositive RA

      A 2 year study evaluated the efficacy and safey (drug retention)

      Dr. John Cush RheumNow

      3 years 5 months ago
      Abatacept Most Effective Early and in Seropositive RA A 2 year study evaluated the efficacy and safey (drug retention) of subcutaneous ABA in active RA and showed superior responses when ABA was given to biologic-naive and seropositive RA patients. https://t.co/WdZ3YCeGXg https://t.co/4ZjFFrVmSJ
      11.5% of Crohns pts have TNFi use contraindications (either MS, CHF, neoplasia, infx risk, TNFi AE, comorbidities, SLE.

      Dr. John Cush RheumNow

      3 years 5 months ago
      11.5% of Crohns pts have TNFi use contraindications (either MS, CHF, neoplasia, infx risk, TNFi AE, comorbidities, SLE. Alternatively GI survey respondents use ustekinumab (76%), vedolizumab (249%), or tofacitinib (0.5%) https://t.co/NqGOislcIJ https://t.co/tqk3jF3Lxg
      Cochrane metanalysis of sleep meds - 170 trials (36 interventions, 47950 pts). Doxepin, seltorexant, zaleplon well toler

      Dr. John Cush RheumNow

      3 years 5 months ago
      Cochrane metanalysis of sleep meds - 170 trials (36 interventions, 47950 pts). Doxepin, seltorexant, zaleplon well tolerated, but efficacy data is scarce. Benzodiazepines, eszopiclone, zolpidem, were more efficacious, but zolpidem more dropouts due to AEs https://t.co/8mPYmfTAaR https://t.co/DqUFcgq9AR
      Placebo responses are to be expected in rheumatoid arthritis (RA) clinical trials, but are such placebo responses affected by continuing background DMARDs like methotrexate (MTX) even though there was an inadequate response (IR) to MTX? 
      For about one in six people considered healthy with no reports of back pain, lesions were visible on MRI in the lower spinal column and sacroiliac joint, researchers said -- a sign that rheumatologists should be cautious about diagnosing spondyloarthritis (SpA) on the basis of imaging.
      Leflunomide versus azathioprine in lupus nephritis? Study of 215 bx proven LN given either LEF or AZA - Renal flares wer

      Dr. John Cush RheumNow

      3 years 5 months ago
      Leflunomide versus azathioprine in lupus nephritis? Study of 215 bx proven LN given either LEF or AZA - Renal flares were equal (15.7% v 17.8%), as was time to flare (16 mo vs AZA 14 mo); 24-hr proteinuria, creatinine, C3 and C4 improved similarly. https://t.co/FEKwwyoJhZ https://t.co/zUyHXGjpOD
      Rheumatologist Survey:
      What do you rely on MOST in diagnosing Still’s disease?
      Sxs? Labs? Both? Criteria? Fever? Vote

      Dr. John Cush RheumNow

      3 years 5 months ago
      Rheumatologist Survey: What do you rely on MOST in diagnosing Still’s disease? Sxs? Labs? Both? Criteria? Fever? Vote here: https://t.co/L1kyWXf68I
      An open-label, 2 year study evaluated the efficacy and safey (drug retention) of subcutaneous (SC) abatacept (ABA) in active rheumatoid arthritis (RA) and showed superior responses when ABA was given to biologic-naive and seropositive RA patients. 
      Watch: Remote Monitoring Technologies in the Management of RA

      Dr. Antoni Chan interviews Dr. Johannes Knitza at EULAR 2

      Dr. John Cush RheumNow

      3 years 5 months ago
      Watch: Remote Monitoring Technologies in the Management of RA Dr. Antoni Chan interviews Dr. Johannes Knitza at EULAR 2022 https://t.co/SU9SUScHiS https://t.co/YoxQPZH5eQ
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