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      RT @drdavidliew: Sometimes the journey impacts as much as the destination.

      TREAT-EARLIER now @TheLancet:
      pre-RA (CSA+MR

      David Liew drdavidliew

      3 years 4 months ago
      Sometimes the journey impacts as much as the destination. TREAT-EARLIER now @TheLancet: pre-RA (CSA+MRI) DBRCT: po MTX for 1y (+im mpred120x1) vs placebo eventual RA same but persistent benefit at 2y (1y post-MTX cessation): function, Sx, presenteeism, MRI a short thread🧵1/7 https://t.co/64b7us6hvS
      During 2021-22, there was 387,112 deaths due to pneumonia, influenza, or COVID-19. At least 72% were dut to COVID-19 and

      Dr. John Cush RheumNow

      3 years 4 months ago
      During 2021-22, there was 387,112 deaths due to pneumonia, influenza, or COVID-19. At least 72% were dut to COVID-19 and 0.6% was due to influenza https://t.co/0ljpXJt0yr https://t.co/1Sp4RULVAY
      Are you treating “systemic” or “articular” (arthritis) Still’s disease? Most Still’s patients have a dominance of one or the other. With certainty, the right therapy for the right symptoms can be chosen. What about patients who have an incomplete or no response, or who become unresponsive to a drug that once worked well?
      Rheums: Got a Rheumatology question or case for Jack Cush? Record it here and we'll feature it on an upcoming podcast.

      Dr. John Cush RheumNow

      3 years 4 months ago
      Rheums: Got a Rheumatology question or case for Jack Cush? Record it here and we'll feature it on an upcoming podcast. Tell us your name and where you practice rheumatology. https://t.co/QUTIbK3r89 https://t.co/FZcTLREida
      Dr. Jack Cush covers the news and journal reports from the past week on RheumNow.com. This week we have Insights NAFLD, overdose deaths, septic arthritis, refractory stills, & when MTX doesn’t work.
      The Still’s ContinuaThe concept of a “Still’s disease continuum” that encompasses both sJIA and AOSD is based

      Dr. John Cush RheumNow

      3 years 5 months ago

      The Still’s Continua The concept of a “Still’s disease continuum” that encompasses both sJIA and AOSD is based on the many common clinical, genetic and laboratory features shared by both sJIA and AOSD. https://t.co/XvtzGBX4MS https://t.co/WJC8U9JNXO

      NHANES Cross-sectional study of 5672 psoriasis US adults (20-59 yrs) shows more NAFLD in PSO patients (33% vs 27% nonPSO

      Dr. John Cush RheumNow

      3 years 5 months ago
      NHANES Cross-sectional study of 5672 psoriasis US adults (20-59 yrs) shows more NAFLD in PSO patients (33% vs 27% nonPSO) with an increased risk (OR 1.67) - moreso in men (OR 2.16), age 20-39 yrs (OR 2.48) & those without diabetes (OR 1.70) https://t.co/VfaJbMKboP https://t.co/dJlcLexDtn
      Patients and their family for years have been inviting me to their dinners, picnics, baptisms, anniversaries, and funerals. I always felt somewhat awkward when asked to participate in a patient’s life outside of my office or the hospital setting and usually will decline politely. I tell myself I should not blur the lines between patient care and friendship. I broke this rule recently.
      Rheumatologist Survey:
      What do you rely on MOST in diagnosing Still’s disease?
      Sxs? Labs? Both? Criteria? Fever?

      Vot

      Dr. John Cush RheumNow

      3 years 5 months ago
      Rheumatologist Survey: What do you rely on MOST in diagnosing Still’s disease? Sxs? Labs? Both? Criteria? Fever? Vote here: https://t.co/oANKpKqJA5 https://t.co/LIjRSBHNBi
      Overdose deaths increased to 107 000 deaths in US in 2021, with significant racial disparity. Higher overdose rates s

      Dr. John Cush RheumNow

      3 years 5 months ago
      Overdose deaths increased to 107 000 deaths in US in 2021, with significant racial disparity. Higher overdose rates seen in American Indian, Alaska Natives and Blacks. WORSE during COVID - 2020, overdose rates were 7 times higher in Blacks than Whites https://t.co/kuXmskZKbB https://t.co/jPkIYrMnSN
      Metanalysis of 9 studies (RCTs, observational) looked @ DMARD effect (most Rx w/ biologics: TNFi, TCZ, RTX, Tofa) on lea

      Dr. John Cush RheumNow

      3 years 5 months ago
      Metanalysis of 9 studies (RCTs, observational) looked @ DMARD effect (most Rx w/ biologics: TNFi, TCZ, RTX, Tofa) on lean & appendicular mass; shows despite bDMARD efficacy - no change in muscle mass! How will UR pts get STRONG? https://t.co/L7bRzPy02i https://t.co/gm5UZYOOeC
      2015 NEJM study of 4g acetaminophen vs PBO in 700 critically ill ICU patients with fever ≥38°C, showed Tylenol vs PBO

      Dr. John Cush RheumNow

      3 years 5 months ago
      2015 NEJM study of 4g acetaminophen vs PBO in 700 critically ill ICU patients with fever ≥38°C, showed Tylenol vs PBO had no differences in mortality, ICU stay or LFTs. Tylenol had small but signif reduction in Temp (38.4±1.0°C vs. 38.6±0.8°C; P<0.001) https://t.co/qnHgFRp20M https://t.co/2E4ZEsIFUV
      TNR: Still's Now Journal Club
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