Dr. Antoni Chan synovialjoints
3 years 6 months ago
Beyond capillaroscopy, US vascular imaging dorsal/ventral fingers can improve detection of vasculopathy of SSc in patients with Rayanaud's (RP) by Nam et al. The % vascular areas in patient's with RP was significantly lower in SSc vs normal volunteers #EULAR2022 @RheumNow POS0127
Robert B Chao, MD doctorRBC
3 years 6 months ago
Methotrexate plus leflunomide combination therapy for PsA treatment resulted in greater improvement in disease activity when compared to MTX monotherapy. As expected, MTX+LEF less well tolerated.
@RheumNow #EULAR2022 ABST#0078 https://t.co/Bo64QX3Bf9
Robert B Chao, MD doctorRBC
3 years 6 months ago
Women with spondyloarthritis at increased risk of gestational diabetes, elective and emergency C-sections, and spontaneous pre-term birth. Infants were not more likely to be born SGA.
@RheumNow #EULAR2022 ABST#OP0126 https://t.co/BTXQqruvPs
Robert B Chao, MD doctorRBC
3 years 6 months ago
Study of 2.9k offspring exposed to adalimumab, infliximab, golimumab during pregnancy, as compared to etanercept and certolizumab showed an adjusted hazard ratio for serious infections of 1.20 (CI 0.54, 2.64).
@RheumNow #EULAR2022 ABST#OP0130
Md Yuzaiful Md Yusof Yuz6Yusof
3 years 6 months ago
#OP0146 #EULAR2022 Is Anti-Ro(52) ab+ on isolation clinically significant? A study of 300 #Sjogren patients showed milder tissue inflammation but a higher risk for fibrosis (lungs) in this group. Interesting to see transcriptomic analysis to identify appropriate target @RheumNow https://t.co/vdxedCI2pk
Dr. John Cush RheumNow
3 years 6 months ago
Are TYK2 inhibitors ‘ticked’ to be part of the JAK family?
Are Tyk2 inhibitors JAK inhibitors?
Yes, no, maybe
Check out all of Dr. Janet Pope’s TYK2 Q&A.
https://t.co/IqeGqt6M4t https://t.co/kjWLVKVFP7
Dr. Antoni Chan synovialjoints
3 years 6 months ago
Differentiating AS from OCI using CT scanning by Terrier et al showed that Subchondral Bone Attenuation Coefficient (SBAC) was higher in OCI than AS with a threshold of >7500 Hounslow Units discriminating the two conditions #EULAR2022 @RheumNow POS0126 https://t.co/8MdSe3Dqp7
Dr. Antoni Chan synovialjoints
3 years 6 months ago
Measuring liver stiffness (LS) by transient elastography can detect and follow up hepatic involvement in AL amyloidosis as radiolabelled SAP scan not widely available by Brunger et al . Higher LS in with liver involvement vs heart/no involvement #EULAR2022 @RheumNow POS0124
Robert B Chao, MD doctorRBC
3 years 6 months ago
GM-CSF increased in patients with active ankylosing spondylitis, correlates with disease activity, not duration. TNFi does not affect GM-CSF levels. Could explain efficacy of JAKinibs and response for residual inflammation during TNF blockade.
@RheumNow #EULAR2022 ABST#OP0107
Dr. Antoni Chan synovialjoints
3 years 6 months ago
Depression was the most prevalent comorbidity (31%), hypertension (26%) and uveitis the most common EMM (30%) in AS from the PSOAS cohort by @rheum_cat .
Five clusters identified with depression and hypertension groups having higher disease activity #EULAR2022 @RheumNow OP0154 https://t.co/dpqaFD4Qzw
David Liew drdavidliew
3 years 6 months ago
Check out my thoughts on this work on PMR's immunol signature:
video: https://t.co/7aTJMsR9Te
article: https://t.co/PTDHPv7gZC
for @RheumNow's #EULAR2022 coverage
PS just had a quick chat with @jiemy_william, so much exciting stuff to come from @VasculitisUMCG @ElisabethBrouw3! https://t.co/l94F5qAgDI
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