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      The US Preventive Services Task Force (USPSTF) has updated its recommendations regarding the efficacy of supplements or multivitamins for reducing the risk of cardiovascular disease, cancer, and mortality in the general adult population.
      Of the Top 20 most expensive drugs in USA in 2022, only two are for rheumatic reasons. Unfortunately both are for ACTH p

      Dr. John Cush RheumNow

      3 years 5 months ago
      Of the Top 20 most expensive drugs in USA in 2022, only two are for rheumatic reasons. Unfortunately both are for ACTH preparations, once cheap, now devastatingly expensive: #11 Acthar Gel ($41,459/month) & #19 Cortrophin Gel ($30,083) https://t.co/avUZNVnHRp https://t.co/mXLhD8vJ6A
      Pooled data from two large ixekizumab (IXE) trials show that male patients had greater clinical responses than did female patients with psoriatic arthritis are largely unexplored. Reasons for this differential treatment responses to an interleukin-17A inhibitor (IXE) between male and female patients is unexplained.
      Study of new onset #RA & undiff arthritis pts starting Rx 2005-2010; mean F/U 104 mos, 11% died. Steroids (<7.5/d

      Dr. John Cush RheumNow

      3 years 5 months ago
      Study of new onset #RA & undiff arthritis pts starting Rx 2005-2010; mean F/U 104 mos, 11% died. Steroids (<7.5/d) given to 44% initially, ultimately 57% w/ 20% recv >7.5/d. Steroids did not increase mortality (HR 1.35 ; 0.74, 2.47) or hospitalization https://t.co/KNpobs1UwH https://t.co/sjddMBKOeE
      RT @OGdukeneurosurg: A reflex slide I put together for you. https://t.co/HMumN7WaJY

      Oren Gottfried, MD OGdukeneurosurg

      3 years 5 months ago
      A reflex slide I put together for you. https://t.co/HMumN7WaJY
      RT @sarahthelyon: Renal Tubular Disorders #NephTwitter #MedEd #MedDoodles https://t.co/KiCuEaDGrR

      Sarah Lyon sarahthelyon

      3 years 5 months ago
      Renal Tubular Disorders #NephTwitter #MedEd #MedDoodles https://t.co/KiCuEaDGrR
      It's time to exonerate methotrexate in causing or exacerbating fibrotic interstitial lung disease in #RA patients https:

      Dr. John Cush RheumNow

      3 years 5 months ago
      It's time to exonerate methotrexate in causing or exacerbating fibrotic interstitial lung disease in #RA patients https://t.co/AuEIWn8Pc4 https://t.co/razVTF6fFX
      Simultaneous Versus Staged Knee Arthoplasty?

      There are an estimated 900,000 knee replacements (TKR) performed in the U.

      Dr. John Cush RheumNow

      3 years 5 months ago
      Simultaneous Versus Staged Knee Arthoplasty? There are an estimated 900,000 knee replacements (TKR) performed in the U.S. every year. This number is up from 754,000 TKRs in 2017, according to the Agency for Healthcare Research and Quality. https://t.co/KuLEaI3r0d https://t.co/0q1RBsDwEM
      Drug Targeting in Psoriatic Arthritis
      • Bruce Kirkham, MD
      FDA approved Abbvies risakizumab-rzaa (Skyrizi) as the 1st interleukin-23 inhibitor for use in adults with moderately to

      Dr. John Cush RheumNow

      3 years 5 months ago
      FDA approved Abbvies risakizumab-rzaa (Skyrizi) as the 1st interleukin-23 inhibitor for use in adults with moderately to severely active Crohn's disease (600 mg IV at wk 0, 4, 8, &q8wk @ 360 mg SC). Approval based on ADVANCE, MOTIVATE & FORTIFY RCTs https://t.co/OMYNB1yr2R https://t.co/QMn9GWlYm9
      JAK/STAT pathway in pyoderma gangrenosum: a new therapeutic highway?Pyoderma gangrenosum (PG) is rare, but often assoc

      Dr. John Cush RheumNow

      3 years 5 months ago

      JAK/STAT pathway in pyoderma gangrenosum: a new therapeutic highway? Pyoderma gangrenosum (PG) is rare, but often associated with different forms of arthritis, in particular rheumatoid arthritis and inflammatory bowel diseases. https://t.co/SvkcZwqzBo https://t.co/M3BkoF4amb

      Metanalysis of 7 studies shows that oral anticoagulants need not be discontinued for joint injections or aspiration. Onl

      Dr. John Cush RheumNow

      3 years 5 months ago
      Metanalysis of 7 studies shows that oral anticoagulants need not be discontinued for joint injections or aspiration. Only pts w/ hemorrhage after 5427 procedures, over 32-yrs. INR values of 3 bleeding cases was 1.9, 2.3, and 3.4. https://t.co/pCxDqzXGHQ https://t.co/ExZkXSliFo
      Modest Benefits of Diet on Arthritis

      A EULAR taskforce reviewed the literature on the effects of diet and lifestyle beh

      Dr. John Cush RheumNow

      3 years 5 months ago
      Modest Benefits of Diet on Arthritis A EULAR taskforce reviewed the literature on the effects of diet and lifestyle behaviors in RMDs, and found little evidence suggesting dietary factors can substantially affect the outcomes in people with RMDs. https://t.co/D31l7dlq9v https://t.co/Kt80Yp74ro
      RT @Janetbirdope: #Leadership = serving your team, being the fall guy, getting group through crazy unnecessary beaurocra

      Janet Pope Janetbirdope

      3 years 5 months ago
      #Leadership = serving your team, being the fall guy, getting group through crazy unnecessary beaurocracy, and loving something about each member of the group. Having their back, sacrificing for them. I can only strive to lead....
      Treatment of pyoderma gangrenosum is clinically empiric. Full read ref w/ Graded Rx Recommendations:
      - 1st line: Steriod

      Dr. John Cush RheumNow

      3 years 5 months ago
      Treatment of pyoderma gangrenosum is clinically empiric. Full read ref w/ Graded Rx Recommendations: - 1st line: Steriods or Cyclosporin - Consider biologics: TNFi, IL-1, IL-12/23, IL-17, IL-23 - Others: MTX, MMF, AZA, Dap, colchic, thalidomide, IVIG https://t.co/uMJyfFzsRB https://t.co/vw4VqbjZWh
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