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      EMA in Europe has approved Rinvoq (upadacitinib 45 mg and 15 mg and 30 mg) for the treatment of adult patients with mode

      Dr. John Cush RheumNow

      3 years 4 months ago
      EMA in Europe has approved Rinvoq (upadacitinib 45 mg and 15 mg and 30 mg) for the treatment of adult patients with moderately to severely active ulcerative colitis who are DMARD-IR or biologic-IR. Based on 3 phase III trials. https://t.co/BjvUm0wPNk https://t.co/IVisAgD1wZ
      BSRBR mandates LFTs q3 mos if on MTX. 1011 RA pts during the pandemic had median of 5 blood tests & median interval

      Dr. John Cush RheumNow

      3 years 4 months ago
      BSRBR mandates LFTs q3 mos if on MTX. 1011 RA pts during the pandemic had median of 5 blood tests & median interval of 57 days. 61% pts had 1 prolonged interval (99-150d) & 24% had multiple. Cytopenia & ^LFTs were not increased by interval length https://t.co/VqY4qIMvOS https://t.co/HcTcmFBuvq
      210 consecutive #RA pts starting #MTX looked at effect of autoantibodies on drug response. DAS28-CRP low dz activity at

      Dr. John Cush RheumNow

      3 years 4 months ago
      210 consecutive #RA pts starting #MTX looked at effect of autoantibodies on drug response. DAS28-CRP low dz activity at 6 mos was significantly lower with SSA+ (56% v 76%, P=0.03) - which was more significant than CCP+ or RF+ https://t.co/DoEtldBXi4 Figures https://t.co/yIECjLiEwl
      The Johns Hopkins Hospital has repeated its top rank among US Rheumatology centers - ranking #1 for the 18th year in a row, according to U.S. News & World Report’s 2022–23 Best Hospitals list released yesterday.
      Have you checked out our new sister-site, Still's Now? A new site for Still's disease, autoinflammatory & febrile d

      Dr. John Cush RheumNow

      3 years 4 months ago
      Have you checked out our new sister-site, Still's Now? A new site for Still's disease, autoinflammatory & febrile disorders. https://t.co/oWEugnOB6k https://t.co/5jwiP2Xqrz
      RT @EricTopol: Every moderately to severely immunocompromised person should know about Evusheld, a preventive Rx. It's u

      Eric Topol EricTopol

      3 years 4 months ago
      Every moderately to severely immunocompromised person should know about Evusheld, a preventive Rx. It's uncommonly prescribed by doctors and there's a general lack of awareness. Still works vs BA.5 An excellent patient page @JAMA_current https://t.co/Exn82D8712 @AnuMalaniMD https://t.co/Rpdhcgg33h
      Management of arthralgias before a certified rheumatoid arthritis (RA) diagnosis is challenging - should one use DMARD therapy before clinically evident synovitis in a preemptive effort to avoid or forestall the diagnosis or damage of RA?
      Patients with interstitial lung disease (ILD) related to systemic sclerosis continued to see less progression when treated with nintedanib (Ofev) in the pivotal 100-week SENSCIS trial, researchers said.
      Risk of hospitalized infection (SIE) goes up with #RA disease activity. Study of 3,254 RA Pts with 529 SIE - SIE rates

      Dr. John Cush RheumNow

      3 years 4 months ago
      Risk of hospitalized infection (SIE) goes up with #RA disease activity. Study of 3,254 RA Pts with 529 SIE - SIE rates lowest with remission (3.8/100PY), vs low dz activity (6.6/100PY; OR 1.60) vs moderate activity (8.8/100PY; OR 183) https://t.co/EWbX7N7fiG https://t.co/Y8bRn2XATF
      New download available on the diagnosis & treatment of Still's Disease.

      Register on RheumNow and download for immed

      Dr. John Cush RheumNow

      3 years 4 months ago
      New download available on the diagnosis & treatment of Still's Disease. Register on RheumNow and download for immediate use. https://t.co/YvgsEtVHVc https://t.co/N9K0cjfakC
      Transcription factor ETS-related gene (ERG) is an orchestrator of lung capillary homeostasis & repair. Dysfunctiona

      Dr. John Cush RheumNow

      3 years 4 months ago
      Transcription factor ETS-related gene (ERG) is an orchestrator of lung capillary homeostasis & repair. Dysfunctional ERG signaling drives pulmonary vascular aging and persistent fibrosis https://t.co/TMFBa74ob7 https://t.co/n60DwGaa74
      Heterozygous deficiency of Aggrecan (proteoglycan w/in cartilage) gene: manifests as inherited short stature, early-onse

      Dr. John Cush RheumNow

      3 years 4 months ago
      Heterozygous deficiency of Aggrecan (proteoglycan w/in cartilage) gene: manifests as inherited short stature, early-onset osteoarthritis, degenerative disc disease, osteochondritis dissecans, increasing joint pathology over time https://t.co/4iQdNL79oB https://t.co/qxStgE641v https://t.co/EHPJuIeQGt
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