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      QD Clinic- Still's (or Not): Fever, Joint pain & Itchy Eyes

      30 yr. woman with high fevers, itchy eyes and Still's m

      Dr. John Cush RheumNow

      3 years 4 months ago
      QD Clinic- Still's (or Not): Fever, Joint pain & Itchy Eyes 30 yr. woman with high fevers, itchy eyes and Still's manifestations for 6 weeks. Still's or Not? https://t.co/kbzhCxYp7H https://t.co/FEUzdXxHoW
      Not Still’s – Now What?

      Your patient doesn't meet criteria for Still’s disease (AOSD or sJIA), now what should yo

      Dr. John Cush RheumNow

      3 years 4 months ago
      Not Still’s – Now What? Your patient doesn't meet criteria for Still’s disease (AOSD or sJIA), now what should you do or consider? https://t.co/xPXZVzTXJr https://t.co/7hmhXFh6O3
      Krill oil supplements in knee osteoarthritis (OA) was shown to be superior to placebo in reducing knee pain, stiffness and function while increasing the omega-3 index. Krill oil, rich in anti-inflammatory long-chain (LC) omega-3 ( ω–3) PUFAs and astaxanthin, is thought to be safe and now shown to be effective nutritional treatment for mild to moderate knee OA.
      Approach to ILD in Myositis Syndromes

      Mehta et al have published a full read review of managing ILD in patients with in

      Dr. John Cush RheumNow

      3 years 4 months ago
      Approach to ILD in Myositis Syndromes Mehta et al have published a full read review of managing ILD in patients with inflammatory myopathies, a heterogeneous group of syndromes connected by ILD and and increased morbidity and mortality risk. https://t.co/MLBGL2ZqTk https://t.co/cdO2nHAK6h
      Litifilimab, a humanized monoclonal antibody against BDCA2, targets the BDCA2 receptor on plasmacytoid dendritic cells. When administered to patients with cutaneous lupus erythematosus (CLE) was shown reducing disease activity in CLE patients.
      Rheumatic Causes for Fever of Unknown Origin

      Fever of unknown origin (FUO) represents a diagnostic challenge to many p

      Dr. John Cush RheumNow

      3 years 4 months ago
      Rheumatic Causes for Fever of Unknown Origin Fever of unknown origin (FUO) represents a diagnostic challenge to many physicians and while cancer and infectious causes need to be excluded, rheumatic disorders are amongst the most common causes of FUO. https://t.co/2tlibH3SHO https://t.co/QsmkfeGEvb
      The janus kinase inhibitor, upadacitinib, has been shown to significantly improve the signs and symptoms of non-radiographic axial spondyloarthritis (nr-AxSpA), extending the efficacy of UPA beyond classic ankylosing spondylitis.
      Physician Assistant Salaries -Amer Academy of Physician Assoc 2022 Report
      Critical care $122,832
      Emer Med $121,480
      Surg

      Dr. John Cush RheumNow

      3 years 4 months ago
      Physician Assistant Salaries -Amer Academy of Physician Assoc 2022 Report Critical care $122,832 Emer Med $121,480 Surgery $121,400 Cardiology $118,000 Heme/Onc $117,297 Rheumatology $113,000 ID $113,000 GI $113,000 Pulm $112,900 PCP $112,000 https://t.co/14SafbtTGm https://t.co/1yuPI5pAYE
      The FDA has extended its indications for ustekinumab (Stelara) for use in pediatric psoriatic arthritis aged 6 years and

      Dr. John Cush RheumNow

      3 years 4 months ago
      The FDA has extended its indications for ustekinumab (Stelara) for use in pediatric psoriatic arthritis aged 6 years and older. Pediatric PsA makes up 6% of all pediatric inflammatory arthritis pts. https://t.co/vTM4x53n7k https://t.co/aQcuMury2k
      FDA has approved a topical PDE4 inhibitor Roflumilast (Zoryve) a 0.3% cream for use in Plaque Psoriasis (Age 12 and Olde

      Dr. John Cush RheumNow

      3 years 4 months ago
      FDA has approved a topical PDE4 inhibitor Roflumilast (Zoryve) a 0.3% cream for use in Plaque Psoriasis (Age 12 and Older) https://t.co/qDuCgUwmZV https://t.co/c0a7723A1X https://t.co/v5T66iKnvc
      THe microbiome differs between #AS (n 33) and AS-IBD(59) compared to IBD (105) patients. Study comparing feces & int

      Dr. John Cush RheumNow

      3 years 4 months ago
      THe microbiome differs between #AS (n 33) and AS-IBD(59) compared to IBD (105) patients. Study comparing feces & intesting Bx. Microbiome composition correlated with BASDAI and faecal calprotectin (FCP) levels. https://t.co/D4QCVVDK7G https://t.co/OJkeisycg0
      Review of Clinical Trial measures in systemic sclerosis:
      -RCTs focus on skin dz, ILD or Pulm HTN using mod. Rodnan skin

      Dr. John Cush RheumNow

      3 years 4 months ago
      Review of Clinical Trial measures in systemic sclerosis: -RCTs focus on skin dz, ILD or Pulm HTN using mod. Rodnan skin (MRSS), 6-min walk -FVC is surrogate measure for SSc-ILD - Composites: CRISS, the EUSTAR-AI -Future: Skin mRNA biomarkersTHBS1 and COMP https://t.co/KPLiNTSSZA https://t.co/YgvWuMiU4i
      Heterozygous deficiency of Aggrecan (proteoglycan w/in cartilage) gene: manifests as inherited short stature, early-onse

      Dr. John Cush RheumNow

      3 years 4 months ago
      Heterozygous deficiency of Aggrecan (proteoglycan w/in cartilage) gene: manifests as inherited short stature, early-onset osteoarthritis, degenerative disc disease, osteochondritis dissecans, increasing joint pathology over time https://t.co/dQERowhrba https://t.co/q7a38FGEzb https://t.co/TPQmnGPoDw
      Belimumab (Benlysta) has been FDA approved for use in pediatric patients with active lupus nephritis who are receiving s

      Dr. John Cush RheumNow

      3 years 4 months ago
      Belimumab (Benlysta) has been FDA approved for use in pediatric patients with active lupus nephritis who are receiving standard lupus therapy. The approval in kids is for the IV formulation only; SC belimumab is for SLE and LN in adults https://t.co/TKyNDwIUQH https://t.co/6VaMOMfwYi
      Metanalysis of cardiovascular effects of Colchicine: 21 RCTs (15,569 pts shows colchicine was superior to placebo reduci

      Dr. John Cush RheumNow

      3 years 4 months ago
      Metanalysis of cardiovascular effects of Colchicine: 21 RCTs (15,569 pts shows colchicine was superior to placebo reducing CV events; with lower risk recurrent pericarditis (RR 0.50), MACE (RR 0.67), & AFib recurrence (RR 0.68) https://t.co/hksDaCSj02 https://t.co/eGRVqZiBBx
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