Dr. John Cush RheumNow
3 years 4 months ago
Cochrane review of Stem cell transplantation in systemic sclerosis (3RCTs w/ 125 pts). Non‐myeloablative & myeloablative selective HSCT had moderate evidence for improved survival, skin thickness & function. But these had high Serious AE rates. https://t.co/d3CPsKiR88 https://t.co/QgCYBikhyl
In a cross-sectional study of US adults, gout was more prevalent in black adults compared to white adults; possibly explained by sex-specific dietary differences and social determinants of health and clinical factors.
Dr. John Cush RheumNow
3 years 4 months ago
Urine-soluble CD163 as a biomarker in #SLE: usCD163 significantly higher w/ active lupus nephritis & correlates w/ UPCR, disease activity, anti-dsDNA Ab levels and a higher chronic kidney disease stage. https://t.co/Mxe53pCnEF https://t.co/BOspodqpSE
Dr. John Cush RheumNow
3 years 4 months ago
Axial PsA frequency? Study of Derm identified PSO adults w/ chronic LBP, onset <45 yrs, not Rx w/ DMARDs--> 100 pts referred to Rheumatology; 14 pts dx w/ axPsA, 5 w/ peripheral PsA, & 3 w/ both axial & peripheral PsA https://t.co/oVxDcY17ZQ https://t.co/oIOfptskf3
ASAS Official_ASAS
3 years 4 months ago
Let’s look at the timeline of major discoveries in AxSpA genetics, starting with HLA-B27 in 1972 https://t.co/f3AvYJodQj
Peter Nash drpnash
3 years 4 months ago
Intensity and longevity of SARS-CoV-2 vaccination response in patients with immune-mediated inflammatory disease: a prospective cohort study https://t.co/1fiNgBQUbr looks like lower ab response and drops over 6 mths - boosters important in our patients
Dr. John Cush RheumNow
3 years 4 months ago
Global Mortality Rates for PsA, SpA and Colitis
Global age-standardized mortality rate (ASMR) for 1000000 was for 0.13 for AS, 0.04 for PsA, 0.86 for CD and 0.76 for UC.
https://t.co/0cZ9kZsiEM https://t.co/hDHojKBeRQ
Dr. John Cush RheumNow
3 years 4 months ago
NEJM - Lupus Pernio in Sarcoidosis - 71 yoM w/ red nodules on his nose, ears, fingers, and toes. The lungs were clear on auscultation. Angiotensin-converting enzyme level of 102. https://t.co/Vy9XQlRVKl https://t.co/wlyx3D9FzC
Dr. John Cush RheumNow
3 years 4 months ago
Utility of Repeat ENA Antibody Testing
Repeat serologic testing is not uncommon, but is it warranted? A retrospective study shows that repeated testing for autoantibodies to extractable nuclear antigens rarely changes the result or adds a new diagnosis.
https://t.co/ncXqSMz0Qo https://t.co/FxHKjJsga3
Dr. John Cush RheumNow
3 years 4 months ago
Retrospective study of 99 Henoch-Schönlein purpura (HSP) pts complicated by GI bleeding (61 mild; 38 severe). Severe GIB assoc w/ sufmmer Onset, facial rash, HI D-dimer (>0.89 mg/L) & neutrophil-to-lymphocyte ratio (NLR >10.56). https://t.co/sI5LoONWGf https://t.co/ySdswRfkMg
Dr. John Cush RheumNow
3 years 4 months ago
Should you do sural nerve biopsy (SNB) to Dx vasculitis? Study of 91 pts undergoing SNB suggests the SNB must be off sufficient length to improve Dx yield. 40/91 (44%) showed vasculitis. +SNB assoc w/ longer SNB sample, other organ Sxs & +ANCA https://t.co/6S00ySj0fL https://t.co/WbY400YsWX
Dr. John Cush RheumNow
3 years 4 months ago
More Bad Safety News for Xeljanz
Another analysis of the mandatory postmarketing safety study for tofacitinib (Xeljanz) has confirmed what most observers expected: that rates of infection with the drug in RA are higher than with TNF inhibitors.
https://t.co/iCrEofMjBR https://t.co/wAr1AuNGUw
Dr. John Cush RheumNow
3 years 4 months ago
Prospective study of 189 new non-infectious anterior uveitis pts, found a high prevalence SpA (56%), 93% w/ axial SpA, few (7) w/ peripheral SpA. 74/106 were newly Dx SpA. SpA predictors: psoriasis (OR 12.5), B27+ (OR 6.3),^CRP (OR 4.8) & male (OR 2.1) https://t.co/5UvH1oTFTb https://t.co/Zi6hH8q5VY
Dr. John Cush RheumNow
3 years 4 months ago
Lilly has announced that Taltz (ixekizumab) is now available as a Citrate-Free Formulation to reduce injection site pain for patients with psoriasis, psoriatic arthritis, spondyloarthritis & nonradiographic axial spondyloarthritis. https://t.co/mTBl9siLED https://t.co/TCFqdK58dA
Dr. John Cush RheumNow
3 years 4 months ago
We've got a lot to discuss this week: psoriasis; fatigue; sleep; sural nerve biopsies; uveitis and SpA; diet and RA; tofacitinib and the ORAL surveillance study; what not to take with mycophenolate - and more.
https://t.co/ctEQBEQpMn https://t.co/rLB6z2bhWc
Poster Hall