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      Cochrane review of Stem cell transplantation in systemic sclerosis (3RCTs w/ 125 pts). Non‐myeloablative & myeloab

      Dr. John Cush RheumNow

      3 years 4 months ago
      Cochrane review of Stem cell transplantation in systemic sclerosis (3RCTs w/ 125 pts). Non‐myeloablative & myeloablative selective HSCT had moderate evidence for improved survival, skin thickness & function. But these had high Serious AE rates. https://t.co/d3CPsKiR88 https://t.co/QgCYBikhyl
      In a cross-sectional study of US adults, gout was more prevalent in black adults compared to white adults; possibly explained by sex-specific dietary differences and social determinants of health and clinical factors. 
      Urine-soluble CD163 as a biomarker in #SLE: usCD163 significantly higher w/ active lupus nephritis & correlates w/ U

      Dr. John Cush RheumNow

      3 years 4 months ago
      Urine-soluble CD163 as a biomarker in #SLE: usCD163 significantly higher w/ active lupus nephritis & correlates w/ UPCR, disease activity, anti-dsDNA Ab levels and a higher chronic kidney disease stage. https://t.co/Mxe53pCnEF https://t.co/BOspodqpSE
      Axial PsA frequency? Study of Derm identified PSO adults w/ chronic LBP, onset <45 yrs, not Rx w/ DMARDs--> 100 p

      Dr. John Cush RheumNow

      3 years 4 months ago
      Axial PsA frequency? Study of Derm identified PSO adults w/ chronic LBP, onset <45 yrs, not Rx w/ DMARDs--> 100 pts referred to Rheumatology; 14 pts dx w/ axPsA, 5 w/ peripheral PsA, & 3 w/ both axial & peripheral PsA https://t.co/oVxDcY17ZQ https://t.co/oIOfptskf3
      RT @Official_ASAS: Let’s look at the timeline of major discoveries in AxSpA genetics, starting with HLA-B27 in 1972 ht
      3 years 4 months ago
      Let’s look at the timeline of major discoveries in AxSpA genetics, starting with HLA-B27 in 1972 https://t.co/f3AvYJodQj
      RT @drpnash: Intensity and longevity of SARS-CoV-2 vaccination response in patients with immune-mediated inflammatory di

      Peter Nash drpnash

      3 years 4 months ago
      Intensity and longevity of SARS-CoV-2 vaccination response in patients with immune-mediated inflammatory disease: a prospective cohort study https://t.co/1fiNgBQUbr looks like lower ab response and drops over 6 mths - boosters important in our patients
      Global Mortality Rates for PsA, SpA and Colitis

      Global age-standardized mortality rate (ASMR) for 1000000 was for 0.13

      Dr. John Cush RheumNow

      3 years 4 months ago
      Global Mortality Rates for PsA, SpA and Colitis Global age-standardized mortality rate (ASMR) for 1000000 was for 0.13 for AS, 0.04 for PsA, 0.86 for CD and 0.76 for UC. https://t.co/0cZ9kZsiEM https://t.co/hDHojKBeRQ
      NEJM - Lupus Pernio in Sarcoidosis - 71 yoM w/ red nodules on his nose, ears, fingers, and toes. The lungs were clear o

      Dr. John Cush RheumNow

      3 years 4 months ago
      NEJM - Lupus Pernio in Sarcoidosis - 71 yoM w/ red nodules on his nose, ears, fingers, and toes. The lungs were clear on auscultation. Angiotensin-converting enzyme level of 102. https://t.co/Vy9XQlRVKl https://t.co/wlyx3D9FzC
      Utility of Repeat ENA Antibody Testing

      Repeat serologic testing is not uncommon, but is it warranted? A retrospective

      Dr. John Cush RheumNow

      3 years 4 months ago
      Utility of Repeat ENA Antibody Testing Repeat serologic testing is not uncommon, but is it warranted? A retrospective study shows that repeated testing for autoantibodies to extractable nuclear antigens rarely changes the result or adds a new diagnosis. https://t.co/ncXqSMz0Qo https://t.co/FxHKjJsga3
      Retrospective study of 99 Henoch-Schönlein purpura (HSP) pts complicated by GI bleeding (61 mild; 38 severe). Severe G

      Dr. John Cush RheumNow

      3 years 4 months ago
      Retrospective study of 99 Henoch-Schönlein purpura (HSP) pts complicated by GI bleeding (61 mild; 38 severe). Severe GIB assoc w/ sufmmer Onset, facial rash, HI D-dimer (>0.89 mg/L) & neutrophil-to-lymphocyte ratio (NLR >10.56). https://t.co/sI5LoONWGf https://t.co/ySdswRfkMg
      Should you do sural nerve biopsy (SNB) to Dx vasculitis? Study of 91 pts undergoing SNB suggests the SNB must be off suf

      Dr. John Cush RheumNow

      3 years 4 months ago
      Should you do sural nerve biopsy (SNB) to Dx vasculitis? Study of 91 pts undergoing SNB suggests the SNB must be off sufficient length to improve Dx yield. 40/91 (44%) showed vasculitis. +SNB assoc w/ longer SNB sample, other organ Sxs & +ANCA https://t.co/6S00ySj0fL https://t.co/WbY400YsWX
      More Bad Safety News for Xeljanz

      Another analysis of the mandatory postmarketing safety study for tofacitinib (Xeljanz

      Dr. John Cush RheumNow

      3 years 4 months ago
      More Bad Safety News for Xeljanz Another analysis of the mandatory postmarketing safety study for tofacitinib (Xeljanz) has confirmed what most observers expected: that rates of infection with the drug in RA are higher than with TNF inhibitors. https://t.co/iCrEofMjBR https://t.co/wAr1AuNGUw
      Prospective study of 189 new non-infectious anterior uveitis pts, found a high prevalence SpA (56%), 93% w/ axial SpA, f

      Dr. John Cush RheumNow

      3 years 4 months ago
      Prospective study of 189 new non-infectious anterior uveitis pts, found a high prevalence SpA (56%), 93% w/ axial SpA, few (7) w/ peripheral SpA. 74/106 were newly Dx SpA. SpA predictors: psoriasis (OR 12.5), B27+ (OR 6.3),^CRP (OR 4.8) & male (OR 2.1) https://t.co/5UvH1oTFTb https://t.co/Zi6hH8q5VY
      Lilly has announced that Taltz (ixekizumab) is now available as a Citrate-Free Formulation to reduce injection site pain

      Dr. John Cush RheumNow

      3 years 4 months ago
      Lilly has announced that Taltz (ixekizumab) is now available as a Citrate-Free Formulation to reduce injection site pain for patients with psoriasis, psoriatic arthritis, spondyloarthritis & nonradiographic axial spondyloarthritis. https://t.co/mTBl9siLED https://t.co/TCFqdK58dA
      We've got a lot to discuss this week: psoriasis; fatigue; sleep; sural nerve biopsies; uveitis and SpA; diet and RA; tof

      Dr. John Cush RheumNow

      3 years 4 months ago
      We've got a lot to discuss this week: psoriasis; fatigue; sleep; sural nerve biopsies; uveitis and SpA; diet and RA; tofacitinib and the ORAL surveillance study; what not to take with mycophenolate - and more. https://t.co/ctEQBEQpMn https://t.co/rLB6z2bhWc
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