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      The ability to prevent RA in individuals at risk is a holy grail in rheumatology. There is a long history dating back to the PROMPT trial of methotrexate and PRAIRIE trial of rituximab. Both otrials showed an effect, but it seemed more likely to be a delaying of RA than prevention or modulation. Framing it another way, there were better outcomes in pre-RA because we were actually treating RA as it emerged with a proven effective treatment. It is
      RT @JulianSegan: Trend of reduced opioid use when initiating biologics and JAKi in RA though effect size small and very

      Julian Segan JulianSegan

      3 years 1 month ago
      Trend of reduced opioid use when initiating biologics and JAKi in RA though effect size small and very high baseline use (>50%) in this insurance claims database. Residual pain and harm minimisation still areas of need. @RheumNow #ACR22 ABST0925 https://t.co/XGHu0fIMF0 https://t.co/PutNNQiKnY
      RT @synovialjoints: JAK and TYK-2 inhibitors and indications in SpA:

      ● Tofacitinib ➣ Pan JAKi (AS, PsA)
      ● Baricit

      Dr. Antoni Chan synovialjoints

      3 years 1 month ago
      JAK and TYK-2 inhibitors and indications in SpA: ● Tofacitinib ➣ Pan JAKi (AS, PsA) ● Baricitinib ➣ JAK1,2 ● Upadacitinib ➣ JAK1 (AxSpA, PsA) ● Deucravacitinib ➣ TYK2 (PsA) Carol Langford, Year in Review #ACR22 @RheumNow https://t.co/EMLEvptySS
      RT @RHEUMarampa: Differences between #uveitis pattern in AS vs. PsA and IBD 👇

      This is always asked to our rheum fell

      sheila RHEUMarampa

      3 years 1 month ago
      Differences between #uveitis pattern in AS vs. PsA and IBD 👇 This is always asked to our rheum fellows during Kelley's hour 🤓 #ACR22 @RheumNow @rheumarhyme @trishiemd @RheumaRamblings @RheumaRambolMD https://t.co/gWxQ9xdb06
      RT @RichardPAConway: Jorge et al. @AprilJorgeMD Incidence SLE nephritis - 16% onset, 35% 15 years. 44.7% men vs 28.6% wo

      Richard Conway RichardPAConway

      3 years 1 month ago
      Jorge et al. @AprilJorgeMD Incidence SLE nephritis - 16% onset, 35% 15 years. 44.7% men vs 28.6% women at 10 years. 40% Black, 38% Hispanic, 40% Asian, 23% White. @RheumNow #ACR22 Abstr#0538 https://t.co/Nbx16jZAN7 https://t.co/BEnAtbcIHt
      Minimal Disease Activity criteria are used to evaluate PsA disease activity and response to treatment. Given that a patient only has to meet 5 of the 7 criteria, should the individual components be weighted equally? 
      RT @RHEUMarampa: GPA pts can have dacryoadenitis (ddx 👇)
      where pt's lateral eye/s can be curved due to swelling.
      How

      sheila RHEUMarampa

      3 years 1 month ago
      GPA pts can have dacryoadenitis (ddx 👇) where pt's lateral eye/s can be curved due to swelling. How to examine? Use thumb to retract eyelid & reveal lacrimal gland underneath, ask pt to look medially #ACR22 @RheumNow @rheumarhyme @doktora_ging @PhRheumaJr #RheumTwitter https://t.co/pJYMffhYWx
      RT @doctorRBC: Deucravacitinib (TYK2 inihibitor) already studied in PsO and PsA, has show efficacy in a phase 2 trial fo

      Robert B Chao, MD doctorRBC

      3 years 1 month ago
      Deucravacitinib (TYK2 inihibitor) already studied in PsO and PsA, has show efficacy in a phase 2 trial for treatment of SLE. Improvement in SRI(4), BICLA, LLADS, CLASI-50 and joint count Abs#1117 @RheumNow #ACR22 https://t.co/XElIuMmud9
      RT @RHEUMarampa: 🦋Only 15% of pts with localized DLE develop SLE
      Risk factors for conversion:
      🔸ANA+ at BL
      🔸dsDN

      sheila RHEUMarampa

      3 years 1 month ago
      🦋Only 15% of pts with localized DLE develop SLE Risk factors for conversion: 🔸ANA+ at BL 🔸dsDNA+ 🔸Gen'd DLE 🔸Cytopenia 🔸Photosensitivity 🔸abn. UA #ACR22 @RheumNow @rheumarhyme https://t.co/n7cKjC1oaR
      RT @RichardPAConway: Tofighi et al. VTE in SLE nephritis. 10% VTE, 5.2% VTE after SLE nephritis diagnosis. Risks - Black

      Richard Conway RichardPAConway

      3 years 1 month ago
      Tofighi et al. VTE in SLE nephritis. 10% VTE, 5.2% VTE after SLE nephritis diagnosis. Risks - Black patients, ds-DNA+, SDI, aPL+, SLEDAI. @RheumNow #ACR22 Abstr#0541 https://t.co/G6q0qvirf7 https://t.co/B8STBTMy14
      A Year in Review
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