Sleep Quality & Psoriatic Arthritis
For people living with psoriatic arthritis (PsA), the comfort of a good night's sleep may feel out of reach for many.
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Ultrasound in PsA
Dr. Arthur Kavanaugh discusses abstract 2206 presented at ACR22 in Philadelphia. Abstract 2206: Understanding Inter-rater Variability in Scoring of Entheseal Lesions: Results from the Diagnostic Ultrasound Enthesitis Tool (DUET) Study
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Tapering TNFi in nonradiographic AxSpA
Dr. Peter Nash at ACR22 Convergence in Philadelphia, PA.
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Sunday (Day 2): ACR 22 Daily Recap
ACR 2022 Daily Recap for Sunday, November 13th. Panelists: Drs. Robert Chao, Antoni Chan, Bella Mehta, Janet Pope, Yuz Yusof, Cassy Sims, Akhil Sood, Sheila Reyes and Jack Cush.
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Spondyloarthritis: Novel Therapies, Diagnostic Dilemmas and Depression
Dr. Lianne Gensler discusses the following abstracts presented at ACR22 Convergence. Abstracts 1597, 1598, 1599 (treatment) and 1613, 1609 and 1614 (diagnosis and outcomes)
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Deucravacitinib in PsA
Dr. Arthur Kavanaugh discusses abstract 1598 at ACR22 Convergence in Philadelphia. Abstract 1598: Safety and Efficacy of Deucravacitinib, an Oral, Selective Tyrosine Kinase 2 Inhibitor, in Patients with Psoriatic Arthritis: 52-Week Results from a Randomized Phase 2 Trial
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Sarilumab in Polymyalgia Rheumatica: Results from SAPHYR Trial
Dr. Michael Putman interviews Dr. Robert Speira about abstract 1676 presented at the ACR22 Convergence meeting in Philadelphia, PA. Abstract 1676: Sarilumab in Patients with Relapsing Polymyalgia Rheumatica: A Phase 3, Multicenter, Randomized, Double Blind, Placebo Controlled Trial (SAPHYR)
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PET CT Imaging to Define Risk of Progression from PSO to PsA
Dr. Peter Nash discusses Abstract 1018 at ACR22 Convergence.
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ACR22 Daily Recap: Saturday Recap
Panelists: Drs. Jack Cush, Michael Putman, Eric Dein, Patricia Harkins and Rachel Tate.
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Richard Conway RichardPAConway
3 years 1 month ago
Kim et al. KOBIO study retention rates b/tsDMARDs in RA-ILD. Lower than in RA without ILD. Smoking (OR 5.2) steroids (OR 0.3) influence. JAKi>tocilizumab>abatacept>TNFi @RheumNow #ACR22 Abstr#0920 https://t.co/ht7IFP7VJe https://t.co/Ul93kcdP5N
Md Yuzaiful Md Yusof Yuz6Yusof
3 years 1 month ago
#ACR22 Abstr#0823 A systematic review which included 36 case series/report showed pulmonary manifestations are common in #VEXAS 56%. Unclear if due to VEXAS or previous disease which was misclassified. Longitudinal study with accurate & timely diagnosis could help @RheumNow https://t.co/ZJvmK2FWrI
Dr. Rachel Tate uptoTate
3 years 1 month ago
Differentiation in UCTD? Abs 0328 finds puffy fingers, abnormal nailfold changes & SSc specific antibodies most predictive for UCTD progression to SSc. Younger age, serositis, +anti-dsDNA antibodies important for progression to SLE. #ACR22 @RheumNow https://t.co/DWL3V3dbFg https://t.co/fYHPOPdzfq
Richard Conway RichardPAConway
3 years 1 month ago
Roongta et al. Small RCT of MTX+LEF vs MTX+RTX in RA. 21 patients each arm. No significant difference. @RheumNow #ACR22 Abstr#0931 https://t.co/jNDrMkkvhP https://t.co/dkfUnh5SM3
Richard Conway RichardPAConway
3 years 1 month ago
Sulli et al. Concommittent folic acid delays MTX response, leads to greater doses of steroids and MTX. But more AEs when MTX without folic acid 32 vs 16% - nausea, transaminase elevations. @RheumNow #ACR22 Abstr#0930 https://t.co/jsUYG2YIZL https://t.co/YOpUbA4Ze9
Dr. Antoni Chan synovialjoints
3 years 1 month ago
IL17i Ixekizumab IXE improved spinal pain at night (SpN) in AxSpA, COAST V 52 wk study
◦ improvement greatest with younger age, HLA-B27+, high disease activity at baseline
◦ associated with improved BASFI, fatigue, SF36
Ramiro S Abs1009 https://t.co/GiCqg7W9IR #ACR22 @RheumNow
Julian Segan JulianSegan
3 years 1 month ago
Occupational inhaled agents increased risk of CCP+ RA, per Swedish occ data (OR 1.25, [1.12-1.38]). Dose-dependent increase in risk. Agents include quartz, asbestos, fungicides & carbon monoxide.
This is a common pt question!
@RheumNow ABST0601 #ACR22
https://t.co/QbsSLIXNar
Richard Conway RichardPAConway
3 years 1 month ago
Park et al. MTX discontinuation for 1 week post-influenza vaccine non-inferior to 2 week hold. Higher flare rate with 2 week hold. @RheumNow #ACR22 Abstr#0936 https://t.co/G53mcWFK2C https://t.co/VFY9TS5OIv
Eric Dein ericdeinmd
3 years 1 month ago
Ab409 #ACR22 Bimekizumab (IL17A, IL17F) & PROs
P Mease on BE MOBILE 1 & 2
BKZ 160 mg q4w vs PBO
254 pts w nr-axSpA, 332 w AS
Improvement in spinal pain, nocturnal pain, morning stiffness, FACIT-FATIGUE for pts with AS and nr-axSpA, statistically signif diff at WK 16
@RheumNow https://t.co/nxZFSrb2XK
Eric Dein ericdeinmd
3 years 1 month ago
Ab1044 #ACR22 Combined Biologic or Targeted Therapy (CBTT) in SpA
31 CBTT courses in 29 SpA pts - 69% also w IBD
Most common: TNF+IL12/23 or IL17
12 pts (38%) d/c CBTT - 7 inefficacy (5 2/2 IBD), 2 for AEs, 3 for other causes. 2 serious AEs (pulm infiltrates, staph ifn)
@RheumNow https://t.co/zExkpam0zK
Richard Conway RichardPAConway
3 years 1 month ago
Reid et al. Safety of immune checkpoint inhibitor combo vs mono in pre-existing autoimmune disease. No significant difference. But 59% vs 32% for irAEs and 23% vs 10% for high grade irAEs @RheumNow #ACR22 Abstr#0757 https://t.co/UYhRM4xO9r https://t.co/r4NurxXzGZ
Richard Conway RichardPAConway
3 years 1 month ago
Bilal et al. Increased risk VTE in aPL+ SLE patients on estrogen vs progesterone contraceptive. All forms progesterone appears equally safe (differs ACR guidance which does not recommended IM or implant) @RheumNow #ACR22 Abstr#0943 https://t.co/HGuZJgaRZQ https://t.co/KrIaKaYNTy
Dr. John Cush RheumNow
3 years 1 month ago
7pm ET on 11/13, join our SLE panel. #ACR22
https://t.co/B8XdaJFLS2 https://t.co/kqJRI2QRms
David Liew drdavidliew
3 years 1 month ago
It's brilliant lab work @MayoClinic that had led the way for JAKi in GCA in clinical trials.
A compelling bench-to-bedside story by @MdWarrington, Dr. Weyand, Dr. Koster and team, and definitely a space to watch
#ACR22 @RheumNow https://t.co/2acKFrWOUF
Poster Hall