Sleep Quality & Psoriatic Arthritis
For people living with psoriatic arthritis (PsA), the comfort of a good night's sleep may feel out of reach for many.
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Ultrasound in PsA
Dr. Arthur Kavanaugh discusses abstract 2206 presented at ACR22 in Philadelphia. Abstract 2206: Understanding Inter-rater Variability in Scoring of Entheseal Lesions: Results from the Diagnostic Ultrasound Enthesitis Tool (DUET) Study
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Tapering TNFi in nonradiographic AxSpA
Dr. Peter Nash at ACR22 Convergence in Philadelphia, PA.
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Sunday (Day 2): ACR 22 Daily Recap
ACR 2022 Daily Recap for Sunday, November 13th. Panelists: Drs. Robert Chao, Antoni Chan, Bella Mehta, Janet Pope, Yuz Yusof, Cassy Sims, Akhil Sood, Sheila Reyes and Jack Cush.
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Spondyloarthritis: Novel Therapies, Diagnostic Dilemmas and Depression
Dr. Lianne Gensler discusses the following abstracts presented at ACR22 Convergence. Abstracts 1597, 1598, 1599 (treatment) and 1613, 1609 and 1614 (diagnosis and outcomes)
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Deucravacitinib in PsA
Dr. Arthur Kavanaugh discusses abstract 1598 at ACR22 Convergence in Philadelphia. Abstract 1598: Safety and Efficacy of Deucravacitinib, an Oral, Selective Tyrosine Kinase 2 Inhibitor, in Patients with Psoriatic Arthritis: 52-Week Results from a Randomized Phase 2 Trial
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Sarilumab in Polymyalgia Rheumatica: Results from SAPHYR Trial
Dr. Michael Putman interviews Dr. Robert Speira about abstract 1676 presented at the ACR22 Convergence meeting in Philadelphia, PA. Abstract 1676: Sarilumab in Patients with Relapsing Polymyalgia Rheumatica: A Phase 3, Multicenter, Randomized, Double Blind, Placebo Controlled Trial (SAPHYR)
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PET CT Imaging to Define Risk of Progression from PSO to PsA
Dr. Peter Nash discusses Abstract 1018 at ACR22 Convergence.
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ACR22 Daily Recap: Saturday Recap
Panelists: Drs. Jack Cush, Michael Putman, Eric Dein, Patricia Harkins and Rachel Tate.
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Dr. Rachel Tate uptoTate
3 years 1 month ago
In clinic US guided entheseal biopsy? Abs 1025 at #ACR22 recommends the lateral epicondyle tendon plate in PsA pts. @RheumNow https://t.co/VomyFkecLq
Dr. Rachel Tate uptoTate
3 years 1 month ago
Exposure to DMARDs prior to ICI treatment was not associated with 2-year crude mortality rates. Abs 0764 #ACR22 @RheumNow https://t.co/WvTy84Si7u https://t.co/X4RvYAVSMC
Aurelie Najm AurelieRheumo
3 years 1 month ago
Window of opportunity in PsA
CorEvitas registry:
Early initiators had more severe disease & worse PROs
but if DMARD therapy initiated within 1 yr: RR=2 MDA achievement & higher reduction of CDAI
https://t.co/Xm9i7aiq85
Abs#1493 #ACR22 @Rheumnow https://t.co/RAGoHeuSIg
Aurelie Najm AurelieRheumo
3 years 1 month ago
Performance BASDAI & ASDAS in evaluating PsA axial symptoms?
400+ pts DISCOVER 1&2
Weak correlations w/ peripheral arthritis
Moderate/strong correlations w/ fatigue & pain
Both perform similarly but do they perform well enough?
https://t.co/alnrEXtydp
Abs#1037 #ACR22 @Rheumnow https://t.co/Zuf1FruneK
Julian Segan JulianSegan
3 years 1 month ago
Benefits with receiving anabolic agents upfront before antiresoprtives (as opposed to other way around). Shame about lack of access to this sequence currently
@RheumNow #ACR22 #osteoporosis https://t.co/S2ttbrVaab
Dr. Rachel Tate uptoTate
3 years 1 month ago
Low likelihood of syndesmophyte formation in PsA but is more likely assoc'd w/ axial involvement radiographically + high CRP. Abs 1014 #ACR22 @RheumNow https://t.co/M5Tc0fd64s https://t.co/e25gwVQKeo
Aurelie Najm AurelieRheumo
3 years 1 month ago
DISCOVER 1 & 2: Subanalysis of GUS in 181 pts w/ Axial PsA and imaging confirmed SI
GUS improves BASDAI, mBASDAI, spinal pain, morning stiffness, and ASDAS from W8 to W24
W24 Response rates BASDAI50 38% BASDAI70 20%
https://t.co/MrS8atrIOI
Abs#1035 #ACR22 @Rheumnow https://t.co/wMDkO1Qak9
Robert B Chao, MD doctorRBC
3 years 1 month ago
Most important point from the Great Debate on treating pre-RA.
Are we really treating to prevent RA or are we simply delaying RA onset?
I don't think there is enough data to treat pre-clinical RA with our current arsenal of DMARDs.
What would you do?
@RheumNow #ACR22
Robert B Chao, MD doctorRBC
3 years 1 month ago
The Great Debate! Should you treat pre-clinical RA?
ACPA+ ~40% did not convert to clinical RA
RF+/ACPA+ least likely to seroconvert to negative
@RheumNow #ACR22 https://t.co/djVPKDdWjz
sheila RHEUMarampa
3 years 1 month ago
Dr. Talabi: Progestin-only has⬇️thrombotic risk vs. estrogen👇
‼️Safety signal for DMPA/depo shot bec. might be more prothrombotic vs. other progestin methods; addt'l studies needed; recommend to avoid in aPL+ for now
#ACR22 @Rheumnow https://t.co/pQe5H8wqvi
TheDaoIndex KDAO2011
3 years 1 month ago
"Less than 1 in 6 rheumatology guideline recommendations are informed by head-to-head RCTs." #ACR22 abst#1284 @rheumnow Comparative Effectiveness Randomized Controlled Trials in Rheumatology Guidelines https://t.co/l5NzzcHRSA
Dr. Rachel Tate uptoTate
3 years 1 month ago
Most prevalent locations of enthesitis on the global SpA population are the lumbar spinous processes, the thoracic spinous processes & Achilles tendon. MEI & MASES best capturing axSpA enthesitis. MEI & SPARCC best in pSpA & PsA. Abs 1004 #ACR22 @RheumNow https://t.co/6IbusqHI5d https://t.co/5y5NFthyJz
David Liew drdavidliew
3 years 1 month ago
Tofacitinib in new-onset PMR:
Nice mechanistic data - all the right things line up - leading to promising proof-of-concept study (EAST PMR)
Plenty to tease apart here but real promise to explore in bigger studies
ABST1107 #ACR22 @RheumNow https://t.co/s4ts7lrVtZ
sheila RHEUMarampa
3 years 1 month ago
Dr Iyer shares how ROSCE can teach trainees #telerheumatology using video visits:
☝️ Relevant to career, enhanced self-directed learning
☝️Accdg to ROSCE results, improvement needed on telemed focused exams
🤓Video ROSCE as T-L strat, eval
#ACR22 @RheumNow #MedEd @rheumarhyme https://t.co/kZXMrbwtzW
Julian Segan JulianSegan
3 years 1 month ago
Coming off denosumab is very tricky! No such thing as drug holiday given high risk of rebound fractures. Need to cap with BP but duration uncertain.
@RheumNow #ACR22 #osteoporosis https://t.co/a4VNAI2D49
Poster Hall